Histological research

Live studies demonstrate that osteoblast lineage cells adhere and proliferate on the surfaces microrugose (2).
Live studies confirm that the SLA surface of EasyLine® accelerates the osseointegration process (3).

Download the pubblication of Histological research

2. Histological examination immediately after insertion (time 0), the threads show extensive contact with the host bone.

3. At time 0 the large and widely spaced threads sink into trabecular bone.

4. Soon after the implant the peri-implant threads space is occupied by bone fragments with osteogenic potential.

5. At two weeks inter-thread space is occupied by newly formed trabecular bone in direct contact with the surface of the peri-implant.


  1. M. Franchi, B. Bacchelli, G. Giavaresi, V. De Pasquale, D. Martini, M. Fini, R. Giardino, A. Ruggeri, “Influence of different implant surfaces on peri-implant osteogenesis: histomorphometric analysis in sheep”, J Periodontol 2007 May; 78(5): 879-88
  2. S. Guizzardi, C. Galli, D. Martini, S. Belletti, A. Tinti, M. Raspanti, P. Taddei, A. Ruggeri and R. Scandrolgio, “Different Titanium Surface Treatment Influences Human Mandibular Osteoblast Response”, J Periodontol 2004 Feb; 75(2):273-82
  3. M. Franchi, E. Orsini, A. Trire, M. Quaranta, D. Martini, G.G. Piccari, A. Ruggeri, V. Ottani, “Osteogenesis and morphology of the peri- implant bone facing dental implants”, ScientificWorldJournal 2004 Dec 14; 4: 1083-95
  4. M. Fini, D. Martini, E. Orsini, L. Leonardi, A. Ruggeri, G. Giavaresi, V. Ottani, “Biological fixation of endosseous implants”, Micron 36 (2005): 665–71


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